The C-Gall Trial: A randomised controlled trial comparing laparoscopic cholecystectomy with observation/conservative management for preventing recurrent symptoms and complications in adults with uncomplicated symptomatic gallstones.
Gallstone disease (cholelithiasis) is one of the most common gastrointestinal disorders which currently affects 10-15% of the UK population. Within this group only 1 in 5 patients will need medical treatment for gallstones. One of the main symptoms of gallstones is extreme pain, which is known as binary colic, on the upper right hand side of the abdomen. People can also suffer inflammation of the gall bladder (cholecystitis) which can be treated with painkillers and antibiotics to control the symptoms experienced by the patient.
Until now most of the studies conducted in this area have been centred on the surgical management of the disease. This highlights a need for researchers to compare the watchful waiting/conservative treatment with the more traditional surgical intervention. By doing this it will help patients, surgeons and health professionals understand what is the best treatment for people suffering pain from gallbladder disease but with no further complications due to it. The results from this study will guide future treatment of gallbladder disease and assess the cost-effectiveness into the different methods of management of the disease.
To find out more about this study, click here.
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