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Current use of SHARE

The effect of spironolactone in older people with knee pain due to osteoarthritis

Dundee researchers are testing a novel way to reduce knee pain.  They are looking for people aged 70 years or over in Tayside or Fife with knee pain due to osteoarthritis, who take painkillers.  The study team approached SHARE to help with recruitment.

This study is funded by Arthritis UK

Chief investigator: Professor Marion McMurdo 

SHARE identified 25 individuals initially that would be suitable for the study.



Agreed to participate

Not interested

Didn’t reply
















 Prof Marion McMurdo is happy with the 16 additional participants which were recruited through SHARE (64% success rate !).  

 DIRECT - Innovative Medicines Initiative:      

DIabetes REsearCh on patient straTification.  PI Ewan Pearson. University of Dundee

 Type 2 diabetes patients are a diverse group; in some, the disease progresses rapidly, while in others it takes a slower course. Similarly, a treatment that works well in one patient may prove less effective in another. This has led researchers to acknowledge that there are actually a number of different subtypes of type 2 diabetes. The goal of the IMI-funded DIRECT project is to identify these subtypes and determine most appropriate treatments for them. The project brings together Europe’s leading researchers from academia, healthcare, and the pharmaceutical industry. Total funding for this project is € 43 100 000.  With over 6 million euros coming to Scotland. 

 We used the SHARE resource to support recruitment in our ongoing study DIRECT Diabetes Progression.  We were working to a very tight deadline and had exhausted all other possibilities for patient identification in the timeframe we had available.  We contacted SHARE to see if they could help us.  Within a few days they were able to run a search for potential volunteers using our inclusion criteria.   Some of these SHARE participants had requested to be contacted by letter, some by phone and some by email.  The SHARE administrator quickly got in touch with the ones that had specified contact by phone or email to ask if the study was of interest.  Some of these potential participants were interested and the research team were able to follow up very quickly with those that were interested, as there was little or no delay in the exchange of contact details once the person on the SHARE register had stated an interest.

  Recruitment from SHARE -  The Scottish Health Research Register

 SHARE also wrote to 22 others that had specified being contacted by letter.  Overall 8 potential participants were identified as interested in the study.  We subsequently found that some of these didn’t meet eligibility criteria based on recent biochemistry data or other factors that we weren’t able to include in the original search plan.  Nevertheless we were able to boost recruitment in the vital last month of the open recruitment period. We’d averaged 9 participants enrolled per month for 2 years but in the final month we managed to enrol 20 participants.  As a result we met the recruitment target for the study.  This was important to us; firstly as a matter of pride - but also because our funding for the study was linked to recruitment of a complete cohort.  Many thanks to the SHARE team and to the SHARE register participants for their willingness to sign up to SHARE and for subsequently considering taking part in our research study. 

Anna Barnett, IMI DIRECT programme manager. University of Dundee.