The GoDARTS Study: Genetics of Diabetes Audit and Research in Tayside and Scotland
This study wants to understand the role our genes, and other biological markers, play in developing and managing diabetes. By conducting this research it will hopefully provide some answers to some of the following questions surrounding the disease; why do some people develop the disease and others don't; why does medication work for some groups of patients with diabetes and not for others and why do some people develop the complications associated with diabetes and others don't.
The other aim of this study is to look at Metformin, which is one of the most commonly used drugs to treat type 2 diabetes. It can also be used in the treatment of type 1 diabetes in conjunction with insulin therapy. Metformin has been on the market for over 60 years yet its mechanism of action is not fully understood. Some patients respond well to the treatment and encounter very little problems, whilst others find it does not work for them and causes many side-effects.
If you would like to find out more about this study then please click here.
The DM1 Neuro Study: Structural CNS Change, Neuropsychological Impairment and Sleep Disorder in Myotonic Dystrophy Type 1: A Genotype-Phenotype Study. Queen Elizabeth Univeristy Hospital, Glasgow.
Myotonic Dystrophy is a long term genetic disorder that affects muscle function and is a type of Muscular Dystrophy. With this condition the muscles often contract and are unable to relax which leads to muscle loss and weakness. Type 1 Myotonic Dystrophy is due to a genetic mutation and currently there is no cure.
The severity of symptoms that people with this condition experience often vary. One of the symptoms that people can suffer is poor quality sleep and excessive sleepiness. This can impair concentration and has an impact on employment, relationships and everyday life.
This study is looking to recruit healthy volunteers that are not affected by Type 1 Myotonic Dystrophy to form a control group. Volunteers will be asked to undertake an MRI scan and neuropsychological tests. The researchers will not be testing any treatments, instead they hope to gain a better understanding of how the brain is affected and how the genetic changes impact on the symptoms experienced. This greater understanding of the disease will give researchers valuable information in designing new trials for future treatments.
If you would like to hear more about this study then please click here.
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