Selected region : South East
Date: : 24th Mar 2017

Current Studies:

The GoDARTS Study: Genetics of Diabetes Audit and Research in Tayside and Scotland. Royal Infirmary of Edinburgh & Western General Hospital.

This study wants to understand the role our genes, and other biological markers, play in developing and managing diabetes. By conducting this research it will hopefully provide some answers to some of the following questions surrounding the disease; why do some people develop the disease and others don't; why does medication work for some groups of patients with diabetes and not for others and why do some people develop the complications associated with diabetes and others don't.

The other aim of this study is to look at Metformin, which is one of the most commonly used drugs to treat type 2 diabetes. It can also be used in the treatment of type 1 diabetes in conjunction with insulin therapy. Metformin has been on the market for over 60 years yet its mechanism of action is not fully understood. Some patients respond well to the treatment and encounter very little problems, whilst others find it does not work for them and causes many side-effects.

If you would like to find out more about this study then please click here.

The PIONEER 5 Study: A Trial Investigating the Oral Semaglutide in Subjects with Type 2 Diabetes and Moderate Renal Impairment. Western General Hospital, NHS Lothian.

Diabetes is a disease in which your body does not make enough insulin or cannot use normal amounts of insulin properly. Insulin is a hormone that regulates the amount of sugar in your blood. When you have type 2 diabetes, the insulin in your body is insufficient to maintain a normal blood sugar level, which can cause blood levels to be too high and causes damage to many of the blood vessels and organs in the body.

The kidneys are one of the organs that can be affected by high blood sugar levels. When the blood vessels in the kidneys are injured, the kidneys cannot clean the blood properly and this can cause other complications such as high blood pressure and cardiovascular disease.

The researchers are investigating a study medication called oral semaglutide, which is being developed for treatment of type 2 diabetes and reduced kidney function. It has already been shown that injectable semaglutide helps control blood sugar and researchers would like to see how effective it is in tablet form.

To learn more about this study then please click here.

The CHARIOT:Pro Substudy: The Cognitive Health in Ageing Register: Investigational, Observational & Trial Studies in Dementia Research. Royal Infirmary of Edinburgh, NHS Lothian

Through research it has been found that there are clinical changes in the brains of patients diagnosed with Alzheimer's disease (AD) many years before the onset of the disease. It is during the first early symptoms stage and before the signs of 'Mild Cognitive Impairment' (MCI) are apparent that drug intervention may be most successful.

The purpose of this study is to investigate the cognitive and functional changes in patients at risk of developing MCI due to Alzheimer's disease. Participants in this study will have no personal history or diagnosis of Dementia and are deemed low, medium and high risk for developing MCI. Samples of blood, urine and saliva samples will be taken periodically for over 2 years to study different biomarkers that can be risk factors for Dementia or Alzheimer's Disease.

If you would like to read more about this study then please click here.

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