GEKO study is looking at a possible new treatment for patients who have ongoing pain with knee osteoarthritis. It is being conducted by researchers at Glasgow Royal Infirmary. The study treatment is called genicular artery embolization (GAE). In knee osteoarthritis, extra blood vessels can grow from the normal blood vessel that supplies blood to the knee and this contributes to inflammation and pain in the knee joint. The GAE procedure is designed to reduce pain by blocking the extra blood vessels, while still preserving the larger blood flow to the bone.
If participants are eligible and decide to join the study, they will be randomly assigned to either receive the active treatment (GAE) or a placebo procedure. The procedure is done using local anaesthetic to numb the area. Participants would only need to stay in hospital for a day and will be asked to fill out questionnaires about health and recovery before and after the procedure and then again at 6 weeks, 3, 6 and 12 months after. Reasonable travel expenses will be reimbursed.
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