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EPAD (Alzheimer's Disease)

Changes in the brain may precede symptoms of Alzheimer's dementia by many years, if not decades. Such changes suggest that a very early Alzheimer's disease process has started well before people start developing the typical symptoms of Alzheimer's dementia like memory loss. If this is the case, then it may be possible to identify Alzheimer's disease at a very early stage, and prevent or delay the disease from developing into dementia.

However, with current knowledge doctors can only diagnose Alzheimer's disease in people who already have dementia or are very close to developing dementia. Available treatments are helpful but cannot fully stop the disease from progressing. It is hoped that from doing large studies, it may be possible to identify Alzheimer's disease before the occurence of symptoms when in theory treatments are most likely to be successful in preventing further spread of the disease in the brain.

The EPAD project is a large international study that is looking to understand the different factors involved in developing Alzheimer's dementia, and also help develop new treatments that are hoped to prevent the disease. This is an observational study that will take place over three years with willing participants who have an interest in being involved in a study about Alzheimer's disease.

Please tell us a little bit more about yourself to see whether you may be suitable for this study.

The researchers want to study a large cohort of people to see whether it is possible to identify Alzheimer's disease at a very early stage.

1 . * Are you aged 50-85?
2 . * Do you live in either the Tayside or the Lothian area?
3 . * Do you have a family history of dementia?
4 . * Have you ever been told you have memory problems?